Acute Infection and Early Disease Research Program (AIEDRP) studies how
the human immunodeficiency virus (HIV) causes disease in adults. AIEDRP
is funded by the National Institute of Allergy and Infectious Diseases.
is a multisite network. Each AIEDRP site consists of one or more
universities or hospitals that conduct research with people who have
been recently infected with HIV. Information gathered by AIEDRP
scientists is shared
in meetings and publications to improve HIV
prevention and treatment strategies.
scientists conduct studies to increase our understanding of how HIV
infects humans and how the disease progresses to AIDS. Scientists
believe that events
that occur during acute and early
infection-including the use of antiretroviral medications-may determine
the ultimate course of the disease.
In the first
weeks and months of infection, people develop high levels of HIV
circulating in the blood. This indicates the virus is multiplying
rapidly. Studies have shown that people
with more HIV in their blood
during the first six months of infection are at higher risk of
developing AIDS sooner in the absence of treatment than those who have
People with lower levels
of the virus
generally stay healthy longer. Studies conducted by AIEDRP scientists
investigate ways to keep viral levels low. Some of the studies involve
medication, and others involve close observation of the immune system.
Still other studies involve laboratory research on cellular and
chemical reactions in the presence of HIV.
If you are
interested in participating in an AIEDRP study, please talk
doctor. To find out which AIEDRP sites may be in your area, please view
the Sites page. And if you would like to see the kinds of questions
that drive research in the AIEDRP network, please view our Publications